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Methylene Violet 3RAX

CAS No. 4569-86-2

Methylene Violet 3RAX( —— )

Catalog No. M36845 CAS No. 4569-86-2

Methylene Violet 3RAX, a phenazine dye, is utilized for staining cell mitochondria and has the capability to alter DNA's molecular structure, disrupt DNA modules, and promote reactive singlet oxygen generation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Methylene Violet 3RAX
  • Note
    Research use only, not for human use.
  • Brief Description
    Methylene Violet 3RAX, a phenazine dye, is utilized for staining cell mitochondria and has the capability to alter DNA's molecular structure, disrupt DNA modules, and promote reactive singlet oxygen generation.
  • Description
    Methylene Violet 3RAX is a phenazine dye to stain the mitochondria of cells. Methylene Violet 3RAX can change the molecular structure of DNA, undermine the module of DNA, and induce the generation of the reactive singlet oxygen. Methylene Violet 3RAX shows inhibition for human erythrocyte AChE and human plasma BChE with an Kis of 1.58, 0.51 μM, respectively. Methylene Violet 3RAX has the potential for the research of potential photosensitizers for mitochondrial targeting action in PDT (photodynamic therapy).
  • In Vitro
    Methylene Violet 3RAX shows antitumor activity by cutting off DNA strands in tumour cell.Methylene Violet 3RAX (0-400 μM) significantly enhances cleavage of DNA with over 60% photocleavage activity towards DNA at 300 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4569-86-2
  • Formula Weight
    378.9
  • Molecular Formula
    C22H23ClN4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(CC)(CC)C1=CC=2[N+](=C3C(=NC2C=C1)C=CC(N)=C3)C4=CC=CC=C4.[Cl-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Si Yao, et al. Methylene violet 3RAX-conjugated porphyrin for photodynamic therapy: synthesis, DNA photocleavage, and cell study. RSC Advances. 2022,12, 21004-21013.
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